After working as News Presenter in Sakshi TV, she appeared as TV Anchor in Jabardasth, a comedy show. The show elevated Anasuya career. After this, she got an opportunity to act in film opposite to Akkineni Nagarjuna in Soggade Chinni Nayana. Later, in the same year, she made her debut with Kshanam in which she portrayed a negative lead role. As a known anchor Anasuya has hosted many award shows like, Zee Kutumbam Awards, Star Parivar Awards, and she has hosted Okarikokaru Awards on Zee Telugu thrice. She has also performed at Apsara awards Function and GAMA Awards Dubai. She has also been a part of Devi Sri Prasad US concert hosting it.